Preimplantation genetic diagnosis and screening used in conjunction with IVF treatments appeared in the early 1990s, and since then hundreds of normal, healthy babies have been born using this advanced reproductive technology. PGD is performed for couples who are at risk for passing on inherited genetic disease to their offspring. It has been suggested that screening of embryos for chromosomal abnormalities (PGS) improves the likelihood of a successful pregnancy and birth for couples with infertility related to recurrent miscarriage or unsuccessful IVF cycles.
Patients who also can benefit from PGS/PGD include:
Couples who have a family history of inherited disease
Couples who want to use gender selection to prevent a gender-linked disease
Women who have had repeated failures with IVF
Women with a history of unexplained miscarriage
Women who are more than 40 years old
PGS screens for numeral chromosomal abnormalities while PGD diagnosis the specific molecular defect of the inherited disease. In both PGS and PGD, individual cells from a pre-embryo are analysed during the IVF process. Before the transfer of a pre-embryo back to a woman's uterus, one or two cells are removed from the pre-embryos (8-cell stage). These cells are then evaluated for normality. Typically within one to two days, following completion of the evaluation, only the normal pre-embryos are transferred back to the woman's uterus. In addition, PGS can reduce the risk of multiple pregnancies because fewer embryos are needed for implantation.
Patients who also can benefit from PGS/PGD include:
Couples who have a family history of inherited disease
Couples who want to use gender selection to prevent a gender-linked disease
Women who have had repeated failures with IVF
Women with a history of unexplained miscarriage
Women who are more than 40 years old
PGS screens for numeral chromosomal abnormalities while PGD diagnosis the specific molecular defect of the inherited disease. In both PGS and PGD, individual cells from a pre-embryo are analysed during the IVF process. Before the transfer of a pre-embryo back to a woman's uterus, one or two cells are removed from the pre-embryos (8-cell stage). These cells are then evaluated for normality. Typically within one to two days, following completion of the evaluation, only the normal pre-embryos are transferred back to the woman's uterus. In addition, PGS can reduce the risk of multiple pregnancies because fewer embryos are needed for implantation.
Preimplantation Genetic Screening (PGS) with Parental Support offers a new technology that gives couples the best chance of having healthy babies. Parental Support uses microarray technology to screen all 24 chromosomes and uses a sophisticated bioinformatic algorithm to improve accuracy.
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