Tuesday, 3 May 2011

Pituitary Suppression -

In a natural menstrual cycle, hormones from the pituitary gland (LH & FSH) cause the growth of an egg within a fluid-filled space, or follicle, within the ovary. Although several follicles start to grow each month, in a natural cycle only one will become mature enough to ovulate following a surge of the hormone LH at midcycle.During the suppression cycle, you will be taking Lupron to prevent ovarian cysts and to block spontaneous ovulation during the stimulation cycle.

In contrast, during an IVF cycle it is desirable for several eggs to mature simultaneously. At the same time we do not want an LH surge to trigger early release of these eggs. We therefore use a medication known as a GnRH agonist to temporarily turn off your own LH and FSH secretion. This medication is usually started around day 22 of the menstrual cycle and continues through the stimulation phase. It is given daily, usually by nasal spray or occasionally by injection. Other GnRH agonist regimens or protocols may also be used in specific cases.

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