Just prior to implantation, the developing embryo must "hatch" out of its outer shell (zona pellucida). Some embryos seem to have a thicker shell that may decrease their ability to implant. This may be due to the age of the woman or other unknown reasons.
Assisted hatching is done just prior to embryo transfer, usually on the morning of the third day after egg retrieval. The embryos have usually grown to six or eight cells at this stage. A fine needle is used to puncture the zona pellucida. There is little or no risk of damaging the embryo during the hatching procedure.
Assisted Hatching is done in situations where it is expected to have a thickened zona pellucida, or have had difficulties achieving implantation, such as:
o When the woman is 38 years or older o When we are using cryopreserved (frozen/thawed) embryos
With assisted embryo hatching a small opening is created in the outer shell of the embryo just prior to embryo replacement.
In vitro fertilization (IVF) is a process by which egg cells are fertilised by sperm outside the body, in vitro. IVF is a major treatment in infertility when other methods of assisted reproductive technology have failed. The process involves hormonally controlling the ovulatory process, removing ova (eggs) from the woman's ovaries and letting sperm fertilise them in a fluid medium. For More Detailed Information : IVF matters
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