Monday 30 May 2011

The History of IVF -The Milestones

2003

Live births after vitrification of oocytes in a stimulated in vitro fertilization–embryo transfer program (Yoon TK, Kim TJ, Park SE, Hong SW, Ko JJ, Chung HM, Cha KY. Live births after vitrification of oocytes in a stimulated in vitro fertilization-embryo transfer program. Fertil Steril. 2003;79(6):1323-6) .

First live birth after ovarian stimulation using a chimeric long-acting human recombinant follicle-stimulating hormone (FSH) agonist (recFSH-CTP) for in vitro fertilization (Beckers NG, Macklon NS, Devroey P, Platteau P, Boerrigter PJ, Fauser BC. First live birth after ovarian stimulation using a chimeric long-acting human recombinant follicle-stimulating hormone (FSH) agonist (recFSH-CTP) for in vitro fertilization. Fertil Steril.

Implantation of the human embryo is the limiting factor in the success of IVF. Dr. Barash and Prof. Dekel showed an Increasing implantation rate following endometrial injury, performed by Pipelle curettage as a simple outpatient procedure. (Barash A, Dekel N, Fieldust S, Segal I, Schechtman E, Granot I. Local injury to the endometrium doubles the incidence of successful pregnancies in patients undergoing in vitro fertilization. Fertil Steril.

Normal birth after microsurgical enucleation of tripronuclear human zygotes (Kattera S, Chen C. Normal birth after microsurgical enucleation of tripronuclear human zygotes: Case report.

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