1995
Pregnancies after Testicular Sperm Extraction (TESE) and ICSI in non-obstructive azoospermia. (Devroey P, Liu J, Nagy Z, Goossens A, Tournaye H, Camus M, Van Steirteghem A, Silber S. Pregnancies after testicular sperm extraction and intracytoplasmic sperm injection in non-obstructive azoospermia. Hum Reprod. 1995;10(6):1457-60).
Birth after blastocyst development from IVM oocyte plus ICSI plus Assisted Hatching (Barnes FL, Crombie A, Gardner DK, Kausche A, Lacham-Kaplan O, Suikkari AM, Tiglias J, Wood C, Trounson AO. Blastocyst development and birth after in-vitro maturation of human primary oocytes, intracytoplasmic sperm injection and assisted hatching. Hum Reprod. 1995;10(12):3243-7).
The first report of aneuploidy testing (Munné S, Sultan KM, Weier HU, Grifo JA, Cohen J, Rosenwaks Z. Assessment of numeric abnormalities of X, Y, 18, and 16 chromosomes in preimplantation human embryos before transfer. Am J Obstet Gynecol. 1995;172(4 Pt 1):1191-9; discussion 1199-201 ).
Zenzes from the group of Casper in Toronto demonstrated adverse effects of cigarette smoking on nuclear spindle. (Zenzes MT, Wang P, Casper RF. Cigarette smoking may affect meiotic maturation of human oocytes. Hum Reprod. 1995;10(12):3213-17).
The first report in which spermatids were used to achieve pregnancy. (Fishel S, Green S, Bishop M, Thornton S, Hunter A, Fleming S, al-Hassan S. Pregnancy after intracytoplasmic injection of spermatid. Lancet. 1995, 24;345(8965):1641-2).
Dmitri Dozortsev and coworkers have discovered that oocyte activation during ICSI is triggered by a water-soluble, heat-sensitive, non species specific cytosolic sperm factor. (Dozortsev D, Rybouchkin A, De Sutter P, Qian C, Dhont M. Human oocyte activation following intracytoplasmic injection: the role of the sperm cell. Hum Reprod. 1995;10(2):403-7).
The larget study done in the filed of IVF comparing urinary FSH with Rec-FSH (Out, H.J., Mannaerts, B.M., Driessen, S.G. and Coelingh Bennink, H.J. A prospective, randomized, assessor blind, multicenter study comparing recombinant and urinary follicle-stimulating hormone in in vitro fertilization. Hum. Reprod., 1995: 10, 2534 –2540).
In vitro fertilization (IVF) is a process by which egg cells are fertilised by sperm outside the body, in vitro. IVF is a major treatment in infertility when other methods of assisted reproductive technology have failed. The process involves hormonally controlling the ovulatory process, removing ova (eggs) from the woman's ovaries and letting sperm fertilise them in a fluid medium. For More Detailed Information : IVF matters
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