The History of IVF -The Milestones

2007

Report from McGill Reproductive Center, Canada and Maria Infertility Hospital Seoul, Korea on deliveries after transfer of human blastocysts derived from oocytes matured by In Vitro Maturation (IVM) (Son WY, Lee SY, Yoon SH, Lim JH. Pregnancies and deliveries after transfer of human blastocysts derived from in vitro matured oocytes in in vitro maturation cycles. Fertil Steril.

Introducing the concept of Mild Treatment Strategy for IVF (Heijnen EM, Eijkemans MJ, De Klerk C, Polinder S, Beckers NG, Klinkert ER, Broekmans FJ, Passchier J, Te Velde ER, Macklon NS, Fauser BC. A mild treatment strategy for in-vitro fertilisation: a randomised non-inferiority trial. Lancet. 2007;369(9563):743-9) .

A novel multi-gradient freezing technique for the cryopreswervation of the whole ovary. Thawing the ovary resulted in normal ovarian architecture and no damage to the vascular wall or intima. (Arav and Pasquale 2007 Yale Practice 12:2)

First IVM egg donation pregnancy in North America achieved by McGill Repro­ductive Centre (Holzer H, Scharf E, Chian RC, Demirtas E, Buckett W, Tan SL. In vitro maturation of oocytes collected from unstimulated ovaries for oocyte donation. Fertil Steril.