Wednesday 18 May 2011

The History of IVF

1988

First two babies born after epididymal sperm aspiration for men with congenital absence of the vas deferens and naming of the technique MESA (Patrizio P, Silber S, Ord T, Balmaceda JP, Asch RH. Two births after microsurgical sperm aspiration in congenital absence of vas deferens. Lancet. 1988, 10;2(8624):1364).

Australia’s first IVF surrogate birth.

The first baby birth using subzonal sperm injection at National University of Singapore (Ng SC, Bongso A, Ratnam SS, Sathananthan H, Chan CL, Wong PC, Hagglund L, Anandakumar C, Wong YC, Goh VH. Pregnancy after transfer of sperm under zona. Lancet. 1988; 1;2:790).

Pregnancy was obtained from micromanipulation using zona drilling or mechanical partial zona dissection (Cohen J, Malter H, Fehilly C, Wright G, Elsner C, Kort H, Massey J. Implantation of embryos after partial opening of oocyte zona pellucida to facilitate sperm penetration. Lancet, 1988;16;2:162).

The death of Dr. Patrick Steptoe -March 21 1988. (The Washington Post ,Article: Dr. Patrick Steptoe, 74, Dies; Pioneered Test-Tube Baby Field, March 23, 1988).


The first preclinical evaluation of pronuclear formation by microinjection of human spermatozoa into human oocytes. (Lanzendorf SE, Maloney MK, Veeck LL, Slusser J, Hodgen GD, Rosenwaks Z. A preclinical evaluation of pronuclear formation by microinjection of human spermatozoa into human oocytes. Fertil Steril. 1988 May;49(5):835-42).

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