Sunday 22 May 2011

The History of IVF -The Milestones

1994

The first live birth as a result of IVM following transvaginal ultrasound–guided oocyte collection. (Trounson A, Wood C, Kausche A. In vitro maturation and the fertilization and developmental competence of oocytes recovered from untreated polycystic ovarian patients. Fertil Steril 1994;62(2):353-62).

Development of the first highly purified FSH preparation for use in IVF (Howles CM, Loumaye E, Giroud D, Luyet G. Multiple follicular development and ovarian steroidogenesis following subcutaneous administration of a highly purified urinary FSH preparation in pituitary desensitized women undergoing IVF: a multicentre European phase III study. Hum Reprod. 1994;9(3):424-30). First pregnancy after use of r-hLH (Hull M, Corrigan E, Piazzi A, Loumaye E. Recombinant human luteinising hormone: an effective new gonadotropin preparation. Lancet 1994;30;344(8918):334-5).

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