Below is what I found online about Lupron

Suppression Stage Lupron Depot (leuprolide acetate for depot suspension) is a GnRH agonist -- a hormone that works in two distinct phases. Phase one stimulates the ovaries causing them to produce more of the most potent of the three estrogens produced by women -- estradiol. In phase two the messenger hormones that tell the ovaries to produce estrogen decline dramatically. This causes a significant reduction in estrogen levels, and causes women to experience menopause-like side effects.

During the suppression stage of the IVF cycle, you take a GnRH Agonist (Lupron, Suprefact, Synarel etc.) to suppress your ovarian function.

The average length of time it takes to get suppressed is 10-12 days. .

The side effects from the suppression medication are similar to that of going into menopause. Some women are very sensitive to the effects of the medication while others experience hardly any changes. I may experience some of the following side effects below.

mood swings breast tenderness hot flashes headaches changes in sex drive

Leuprolide is an injectable, man-made hormone that is used for treating prostate cancer, endometriosis, central precocious puberty, and fibroids. It is similar to but stronger than human gonadotropin releasing hormone (GnRH).

GnRH is made in the hypothalamus (a part of the brain)and travels to the pituitary gland where it causes the production of luteinizing hormone (LH) and follicle stimulating hormone (FSH). LH and FSH are released by the pituitary into the blood and stimulate the production of testosterone by the testes in men and estrogens by the ovaries in women. The release of GnRH, LH and FSH is governed by negative feedback which means that when there is too much testosterone or estrogen being produced, the body sends a signal to the pituitary gland to reduce the production of GnRH which, in turn reduces the production of LH and FSH. This results in reduced production of testosterone and estrogen. When given continuously, leuprolide initially increases the production of LH and FSH as well as testosterone and estrogen; however, after a few weeks of continuous leuprolide, the levels of LH and FSH drop because the pituitary gland stops responding to GnRH and leuprolide. This leads to a decrease in the production of estrogen and testosterone.

Testosterone promotes the growth of prostate cancer. Therefore, leuprolide is used in treating prostate cancer to slow the growth of the cancer. In children with central precocious puberty (puberty caused at an early age because of too much LH and FSH) leuprolide, by suppressing LH and FSH, reduces the levels of estrogen and testosterone and allows for more normal timing of puberty. Estrogens promote the growth of fibroids (benign tumors of the uterus) and areas of endometriosis (abnormal uterine tissue that exists outside of the uterus). Leuprolide is used to reduce the production of estrogen and treat both fibroids and endometriosis.